Common Myths About Clinical Trials (And What’s Actually True)


Clinical trials are one of the most important tools we have in advancing medicine—especially in the field of mental health. But if you’ve ever considered participating in a clinical trial, chances are you’ve come across a few myths that made you pause. Words like “risky” or “guinea pig” get thrown around, and suddenly what could be a promising opportunity feels uncertain.

At APG Health, we work closely with families across Orlando, Winter Park, and Altamonte Springs to help them understand the facts about clinical research—so they can make informed, confident decisions about their care. Let’s break down some of the common myths about clinical trials and replace them with the truth.


Myth #1: "Participants Are Just Guinea Pigs"

This is one of the most damaging and outdated common misconceptions about clinical research. The truth is, protecting participants is the top priority in every legitimate research study.

Clinical trials are designed with strict safety protocols and are overseen by ethics boards, regulatory agencies, and licensed professionals. Participants are monitored closely, and care is provided by trained clinicians—not lab technicians in secret labs.

At APG Health, we only refer families to reputable trials that follow the highest ethical standards. If you choose to join a clinical trial, you’ll be treated with the same dignity and attention you’d receive in any high-quality health care setting.


Myth #2: "You Lose All Control Once You Join"

False. The informed consent process exists to protect your rights and ensure you understand every aspect of the study before making a decision.

Before you or your child enrolls, you’ll review a consent form that covers:

  • The purpose of the study
  • What will happen during the trial
  • Possible side effects
  • Your right to leave the trial at any time

You’re never locked in. Participation is always voluntary, and you can withdraw for any reason—without affecting your access to other treatment works or medical services.


Myth #3: "Clinical Trials Are Only for People With No Other Options"

Not true. While some trials are designed for patients who haven’t responded to standard of care, many are open to individuals who are still early in treatment or even just exploring their options.

Participating in a clinical trial can offer access to innovative care that isn’t widely available yet. You may receive new medications, advanced therapies, or extended monitoring—all under expert supervision.

Whether you're managing a long-term mental health condition or looking for alternatives to current medications, we can help you determine if a research study is a good fit.


Myth #4: "The Placebo Means I Won’t Get Any Help"

In many trials, especially those studying new medications, participants are randomly assigned to either a treatment or placebo group. This allows researchers to measure how well the treatment works.

But here's what most people don’t realize: even participants who receive a placebo still get excellent care. You’re not left to struggle or wait—you’re monitored, supported, and have full access to mental health professionals who are watching for any changes.

Plus, not all trials use placebos. Some compare new treatments to standard of care, meaning you’ll receive some form of active treatment no matter what.


Myth #5: "Side Effects Aren’t Disclosed"

The opposite is true. The informed consent process includes a thorough review of known risks and side effects. Researchers are legally required to disclose what is known—and to stop or adjust the study if new risks appear.

You’ll also be monitored closely throughout the trial. If you experience any side effects, you’ll have immediate access to care and the option to adjust or discontinue participation.

At APG Health, we work with local research partners to ensure families in Orlando, Winter Park, and Altamonte Springs receive compassionate, informed support throughout the trial experience.


Myth #6: "You Can’t Trust Clinical Trials"

This myth may come from a place of fear—but the truth is, clinical research is one of the most highly regulated areas of health care. In the U.S., every clinical trial must be reviewed by an Institutional Review Board (IRB) to ensure it meets strict ethical and safety guidelines.

Plus, before a study can even begin enrolling participants, it must demonstrate that the potential benefits outweigh the risks—and that there's a sound scientific reason behind the research.

In short: the process is designed to protect participants and prioritize their well-being.


Clinical Trials: A Window Into the Future of Care

From new medications to breakthrough therapies, every mental health advancement we use today started as a research study. Thanks to people willing to participate, we now have safer, more effective options for managing conditions like ADHD, anxiety, depression, and more.

If you or your child is struggling with symptoms, or if you're curious about treatment alternatives, joining a clinical trial could be an empowering step—not just for your own care, but for others like you.


Want to Explore a Clinical Trial?

If you're considering participating in a clinical trial, or you simply want to learn more about your options, contact APG Health today. We’re here to answer your questions, review eligibility, and connect you with trusted research partners throughout Orlando, Winter Park, Altamonte Springs, and beyond.


Don’t let myths keep you from exploring what’s possible. With the right information and support, clinical trials can be a powerful part of your care journey. Let’s take that step—together.

A woman patient, sitting on the couch during a consultation with a psychologist, talks about her difficulties in life, stress and relationship problems.